The match is over. Score: 0-0. Lyon 5.30| Draw 4.48| Barcelona 1.57 Bet Now With Betway Predictions | Betting Tips | Odds | Statistics Lyon welcome Barcelona to the Groupama Stadium looking to end an abysmal record against the reigning La Liga champions. Predictions After impressing in the group stages, Lyon are a side on a high and will know that if they are to finally break their duck against Barcelona, then now is the time. Five draws and one win was enough to see Bruno Génésio men progress in second place in Champions League Group F to the latter stages but perhaps most impressively was the one win which came at Manchester City, proof enough that Lyon can get themselves up for the big matches. However, Barcelona pose a stern threat no matter how good your form is and it when it comes to playing against Olympique Lyonnais, Barcelona has never lost. That makes the Catalan club favourites to progress with the best betting sites and rightly so. Ernesto Valverde’s Barca side made short work of what was a tough group on paper, comprising Inter, Tottenham and PSV Eindhoven. Four wins and two draws left the five-time European champions undefeated and in dangerous form. Whichever way you look at it, it would be foolish not to favour the Spaniards for the win especially in their six meetings in total Barca has won four and drawn two of them. However, one thing is clear and that is goals should be in abundance as the pair shared a total of 26 in the group stages making a highly entertaining 3-2 scoreline in favour of Barca the way to go. 1×2 Prediction Bet Now With Betway Score Prediction Bet Now With Betway Betting Tips Over 3.5 goals Both sides averaged two or more goals per game throughout the group stages making a goal fest the best way to go with popular sportsbooks for overall excitement and a solid pay out. Lionel Messi to score anytime An obvious choice for goalscorer perhaps hence the odds but considering the Argentine has netted three goals in four games against Lyon, you can see why it is a no-brainer. Odds 1 x 2 Odds Lyon Draw Barcelona 5.30 4.48 1.57 5.50 4.50 1.55 5.25 4.33 1.55 5.50 4.65 1.60 4.25 3.35 0.55 Statistics Head to Head As mentioned above, the pair have met six times in UEFA competition. Most recently was during this stage in the 2008-09 Champions League with Barcelona winning 6-3 on aggregate thanks to a 1-1 draw at Lyon followed up with 5-2 win at the Camp Nou. Lyon has never beaten Barcelona in six attempts with the Catalans recording four wins and two draws. Stats Both sides went through the group stages unbeaten. In six attempts, Lyon has never beaten Barcelona losing four times. Barcelona’s French defender Samuel Umtiti will return to his boyhood club Lyon for the first time since switching to the Catalans in 2016. Lyon have never reached the final of the Champions League whilst Barcelona have won the competition five times. Lionel Messi has scored three goals in his four games against Lyon. Lyon 5.30| Draw 4.48| Barcelona 1.57 Bet Now With Betway Check more Champions League predictions and our additional betting predictions.