Los Angeles Rams Vs San Francisco 49ers: Predictions, Odds and Betting Tips

NFL Los Angeles Rams Vs San Francisco 49ers

NFL Los Angeles Rams Vs San Francisco 49ers

Sunday, 21 October 2018, 4:25 pm Eastern Time
Levi’s Stadium 

Predictions | Betting Tips | Odds | Statistics

200$ To Bet Now With Sports Interaction


The Rams take their undefeated record on the road into San Francisco, to face off with a 49ers team who just went down to the wire with Aaron Rodgers and his Green Bay Packers on Monday night.  


The 49er hopefuls must be extremely disappointed by that heart-wrenching defeat at the hands of Aaron Rodgers Monday night, and understandably so. They showed the world, in a primetime game, that just because Jimmy Garoppolo may be done for the season doesn’t mean they’re just some team you look over on your schedule. Wideout Marquise Goodwin returned from injury in a big way, to the tune of 146 yards and two touchdowns from 67 yards and 30 yards out. Running back Matt Brieda surprised everyone when he was announced as active for the game, and while he scored a touchdown, fellow running back Raheem Mostert was the more impressive back, averaging 7.2 yards on 12 carries.

Los Angeles has continued their winning ways, but they aren’t blowing people out the way they were early in the season. Over the last three games they have won by an average of only 4 points. Jared Goff is coming off of maybe his most disappointing game since the Jeff Fisher era, and Cooper Kupp and his 5 receiving touchdowns will most likely miss this game with a knee injury.

Todd Gurley is coming off a 200 yard rushing performance, and is well on his way to another offensive player of the year award. San Francisco’s 20th ranked defense should struggle to stop Gurley in the rushing game, as well as in the passing game. Brandin Cooks speed should be a huge asset working against the lankier, but stiffer corners of San Francisco. Overall, no one expects San Fran to pull off the upset, but they will keep it interesting.

Score prediction: Rams win 30-23

Betting Tips

The 49ers may have lost three games in a row, but the average defeat margin was only 5 points, while LA has won their last 3 games by a combined average of 4 points. CJ Beathard just went toe to toe with Aaron Rodgers on national TV, and gets a beat up Rams secondary this week. Look for speedster Marquise Goodwin to get over the top of LA defense on multiple occasions.

The Rams are averaging nearly 33 points offensively on the season, but have also surrendered over 26 ppg in their last 4 outings, and over 30 points in two of those games. The 49ers are coming off a 30-point game of their own, and averaged a respectable 24.7 ppg on the season.

200$ To Bet Now With Sports Interaction


Head to Head

Los Angeles may be the current Super Bowl favorites, but their division-mates in San Francisco have owned them in the last 10 games, with a 7-3 record. Most recently winning 34-13 last December.


  • Los Angeles is 5-0 SU in its last 5 road games.
  • The total has gone OVER in 8 of Los Angeles’ past 12 games.   
  • The total has gone OVER in all of San Francisco’s past 5 games.
  • San Francisco is 5-0 ATS in their last 5 games when playing Los Angeles, and 4-1 ATS when playing Los Angeles at home.
  • San Francisco is 7-2-1 SU in its last 10 games when playing Los Angeles at home.
  • Los Angeles’ Todd Gurley leads the NFL in rushing (623 yards) and rushing TDs (9).